BCAA Ethyl Ester Reviews

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BCAA Ethyl Ester
Brian Green
By Brian Green
April 26, 2013

BCAA Ethyl Ester “is a high potency formula containing the essential amino acids L-leucine, L-valine, and L-isoleucine.” These 3 amino acids are the branched-chain amino acids (BCAAs).

Dozens of supplements contain BCAAs, but BCAA Ethyl Ester is said to be different because its BCAAS are “in a revolutionary ethyl ester form and in a specific ratio to maximize their effectiveness.”

Since so many BCAA supplements are similar, I was curious to see if BCAA Ethyl Ester really is better.

How Are BCAAs Supposed to Help?

Amino acids are protein building blocks and protein builds muscle. So, athletes and bodybuilders use products like BCAA Ethyl Ester to enhance muscle growth and speed recovery.

The manufacturer Axis Labs also claims BCAA Ethyl Ester…

• Increases strength
• Releases hormones such as GH, IGF-1, and insulin
• Reduces cortisol secretion
• Prevents catabolism
• Stimulates protein synthesis and energy metabolism

Unfortunately, the body cannot manufacture BCAAs and get these benefits. That’s why Axis Labs created the BCAA Ethyl Ester supplement.

BCAA Ethyl Ester’s Ingredients

Aside from magnesium stearate (flow agent) and gelatin (capsules), the only ingredients in BCAA Ethyl Ester are branched-chain amino acids.

BCAA Ethyl Ester contains the typical ratio for L-leucine, L-isoleucine, and L-valine (2:1:1). I couldn’t find any research to prove this ratio or the following dosages are effective. But, 2:1:1 is the most common ratio in BCAA supplements.

L-Leucine Ethyl Ester (1,600 mg). L-leucine gets the most credit because it is the most studied. Leucine stimulates muscle protein synthesis[1] and prevents catabolism.[2]

L-Isoleucine Ethyl Ester (800 mg). Like L-leucine, L-isoleucine reduces muscle breakdown. It is purported to speed up muscle repair and normalize blood sugar levels, too.[3]

L-Valine Ethyl Ester (800 mg). Valine supposedly preserves, repairs, and builds muscle tissue. Some people also believe the amino acid reduces insomnia and nervousness, and suppresses appetite.[4]

There are several studies involving BCAAs. However, the studies didn’t always use L-leucine, L-isoleucine, and L-valine. Sometimes additional ingredients were used or only 1-2 amino acids were tested. Most studies were performed on animals, not humans.[5][6]

Axis Labs claims BCAAs with ethyl ester attached are more powerful. But, I couldn’t find any research involving L-leucine ethyl ester, L-isoleucine ethyl ester, or L-valine ethyl ester. So, the claim is not supported by research.

Do Users Like BCAA Ethyl Ester?

NutraPlanet.com has 9 ratings and 1 review from users. The average rating was 3.6 out of 5 stars, which is above average. The review said BCAA Ethyl Ester builds strength and enhances recovery, but the reviewer only gave 1 star. This could be a mistake.

Five users gave BCAA Ethyl Ester 9 out of 10 stars on Bodybuilding.com, which is excellent. Unfortunately, no one wrote a review on BCAA Ethyl Ester.

According to 14 ratings, most users like BCAA Ethyl Ester, but 14 ratings is not enough. I need to see more feedback to determine how many users like BCAA Ethyl Ester.

Where to Buy BCAA Ethyl Ester

The BCAA Ethyl Ester bottle holds 180 capsules. The recommended daily dosage is 2 servings (8 capsules) a day, so the bottle lasts 22.5 days.

You won’t find the best deal for BCAA Ethyl Ester on the official website. It charges $47.96 which is less than the retail price but more than most sites charge.


• $28.99 per bottle
• Shipping costs $5.95
• 30-day return policy for used/unused bottles


• $33.48 per bottle
• Shipping costs $5.93
• 45-day return policy for used/unused bottles


• $34.95 per bottle
• Shipping costs $6.95
• Contact the company for return information

Is Axis Labs a Reliable Company?

Axis Labs was started in 2005 with the goal to “produce the best quality sports nutrition supplements on the market.” In 2006, the company went international and now distributes products to 6 continents.

“We aren’t interested in being the biggest company out there, just the best!!” claims AxisLabs.net.

Unfortunately, Axis Labs hasn’t always lived up to its “goals” and “interests.” On January 25, 2012, the company pled guilty to mail fraud charges. The U.S. District Court placed Axis Labs on 1 year of unsupervised probation and fined the company $157,400.

According to the Better Business Bureau, Axis Labs in an A- company.[7] However, BBB’s own reliability is also in question.[8]


BCAA Ethyl Ester costs more than most BCAA supplements, perhaps because Axis Labs believes their product is better. But, I wasn’t convinced.

Axis Labs claims BCAA Ethyl Ester is better because its ethyl-ester-enhanced ingredients are more powerful. But, the company doesn’t provide evidence and I couldn’t find any. In addition, I couldn’t find research to prove BCAA Ethyl Ester releases hormones and reduces cortisol secretion.

BCAA Ethyl Ester may build muscle and speed recovery but so do more-affordable BCAA supplements. I recommend buying an affordable, highly-recommended BCAA supplement rather than BCAA Ethyl Ester.


[1] Blomstrand, E, J Eliasson, et al. “Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise.” Journal of Nutrition. 136. (2006)

[2] “Exercise-Dependent Preference for a Mixture of Branched-Chain Amino Acids and Homeostatic Control of Brain Serotonin in Exercising Rats .” Journal of Nutrition. 136.2 (2006).

[3] “What Is L-Isoleucine?” wiseGEEK. Conjecture Corporation.

[4] “L-Valine Benefits.” TrulyHuge.com.

[5] Rennie, MJ, J Bohe, et al. “Branched-chain amino acids as fuels and anabolic signals in human muscle.” Journal of Nutrition. 136. (2006).

[6] Baptista, IL, ML Leal, et al. “Leucine attenuates skeletal muscle wasting via inhibition of ubiquitin ligases.” Muscle Nerve. 41.6 (2010): 800-8.

[7] “Axis Labs, Inc.” Better Business Bureau.

[8] “Complaint Review: Better Business Bureau BBB & CBBB.” Ripoff Report. 27 Apr 2011.

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