OxyElite Pro Advanced
OxyElite Pro was recently banned by the FDA because of the controversial ingredient DMAA, but OxyElite manufacturers didn’t give up on their popular product. Now, they’ve come out with a new
OxyElite formula: OxyElite Pro Advanced.
Presumably, OxyElite Pro Advanced will be without the powerful—though dangerous—stimulant DMAA. But what else is in this supplement, and will it still be effective?
OxyElite Pro Advanced Formula
With DMAA gone, fans of the original OxyElite Pro might wonder if it’s still powerful enough to cause weight loss. The only way to find out is to look closer at the ingredients:
Proprietary Blend (225 mg)
The main ingredients in the blend are the following:
Olea Europea Leaf Extract. Components of olea europea, or olive, exert an anti-inflammatory effect and may even inhibit growth of certain cancer cells.  It’s clear this ingredient is healthy for consumption, but I was unable to locate human studies of its effect on weight loss. It did stimulate thyroid in rats, which means it has potential to raise metabolic rate, but effects on humans have not been thoroughly examined. 
Yohimbe. Although typically used to treat erectile dysfunction, yohimbe might stimulate weight loss. In fact, two daily doses of 20 mg helped soccer players decrease fat mass and body fat percentage. 
Coleus Forskohlii. In one clinical study, 23 overweight women took 250 mg coleus forskohlii extract two times a day for 12 weeks. Coleus forskohlii did not lower body mass or fat free mass, but it did prevent weight gain. Researchers concluded it might mitigate weight gain but probably does not promote weight loss. 
The blend also contains cynanchum auriculatum and aegeline, but these ingredients are not yet backed by human studies.
Caffeine (100 mg). Caffeine amps fat burning during exercise by increasing heart rate. In one study, 192 mg caffeine a day, with ephedra, decreased body fat and body weight as well as cholesterol levels. However, subjects reported dry mouth, heartburn, and insomnia. 
OxyElite Pro Advanced Side Effects
There’s no DMAA in OxyElite Pro Advanced, but the ingredient to watch out for is yohimbe. It might cause anxiety, insomnia, headache, nausea, and other side effects, and it may increase risk of heart attack, kidney failure, and seizure. 
You shouldn’t take yohimbe if you have medical conditions, including anxiety, depression, heart problems, kidney or liver disease, Alzheimer’s, or blood pressure problems, without first talking to a doctor. 
Caffeine might cause mild side effects in some users like nausea, jitteriness, or increased heart rate. OxyElite Pro Advanced probably doesn’t have enough caffeine to cause side effects in most users, but be sure not to take caffeine from other sources while taking OxyElite Pro Advanced. In fact, the product label warns you to avoid caffeine, alcohol, and stimulants of any kind while taking this supplement.
You should talk to a doctor before using if you have a medical condition or are taking medication. If you experience side effects, discontinue use.
Using OxyElite Pro Advanced
The following steps outline how to use OxyElite Pro Advanced:
1. Consult with a physician
2. Take one capsule on an empty stomach 15 to 30 minutes before breakfast
3. You may take another capsule 5 to 6 hours later
4. If tolerated, another capsule can be added in the morning
5. Do not exceed recommended serving
6. Do not use for longer than 8 weeks without a 4 week break
7. Drink 125 fl. oz. liquid (men) or 91 fl. oz. liquid (women) per day while taking this product
OxyElite Pro Advanced Pricing
So far, OxyElite Pro Advanced is not sold on the official website, although when it is available, the price will be $59.99.
I could only find one location that says OxyElite Pro Advanced is in stock: VitaminShoppe.com, which sells it for $39.99. Other locations say the product will be available in September 2013. Undoubtedly, OxyElite Pro Advanced will soon be available at many locations.
OxyElite Pro Advanced: The Final Word
OxyElite Pro Advanced has some ingredients shown to cause weight loss but nothing that blows it out of the water. Although it is safer than the original formula, there are still plenty of warnings on the label, which makes me wary about potential side effects.
I would wait for customer reviews on the new OxyElite Pro Advanced before buying.
 Syed Haris Omar. “Oleuropein in Olive and its Pharmacological Effects.” Sci Pharm. 2010; 78 (2): 133-154. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002804/#b42-scipharm.2010.78.133
 Al-Qarawi AA et al. “Effect of freeze dried extract of Olea europaea on the pituitary-thyroid axis in rats.” Phytother Res. 2002; 16 (3): 286-7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12164280
 Sergej M. Ostojic. “Yohimbine: The Effects on Body Composition and Exercise Performance in Soccer Players.” Research in Sports Medicine: An International Journal. 2006; 14 (4): 289-299. Available from: http://www.tandfonline.com/doi/abs/10.1080/15438620600987106#.UhUXB5K2N7V
 Shonteh Henderson et al. “Effects of Coleus Forskohlii Supplementation on Body Composition and Hematological Profiles in Mildly Overweight Women.” Journal of the International Society of Sports Nutrition. 2005; 2 (2): 54-62. Available from: http://www.biomedcentral.com/content/pdf/1550-2783-2-2-54.pdf
 Boozer CN et al. “Herbal ephedra/caffeine for weight loss: a 6-month randomized safety and efficacy trial.” International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity. 2002; 26 (5): 593-604. Available from: http://europepmc.org/abstract/MED/12032741/reload=0;jsessionid=Hd4J3pZmA95q6q9CH99Z.8
 “Yohimbe.” WebMD.com. Available from: http://www.webmd.com/vitamins-and-supplements/lifestyle-guide-11/supplement-guide-yohimbe